Pink ribbon and DNA helix representing breast cancer research
A Research Project

Understanding HER2-Positive Breast Cancer

Stage 4 HER2+ breast cancer is a form of metastatic breast cancer that has spread beyond the breast and nearby lymph nodes. The HER2 protein drives faster growth — but also makes the disease responsive to targeted therapy. This project bridges the science with one woman's 19-year lived experience.

15–20%
of breast cancers are HER2-positive
Stage 4
metastatic at diagnosis
19 yrs
survivor & counting
1998
Herceptin (trastuzumab) approved
Three Lenses

Science meets the human story

"
I realized how quickly everything can be taken. Cherish.
— Interview Subject, 19-Year Survivor
HER2 receptor cells under microscope
Why HER2 Matters

A "cell eater" — described by the patient herself

HER2-positive cancers overexpress the human epidermal growth factor receptor 2 — a protein that, in normal amounts, helps regulate cell growth. When overproduced, it drives uncontrolled, rapid division.

This is what makes HER2+ disease so aggressive — and exactly why targeted therapies like Herceptin transformed survival rates after their approval in the late 1990s.

Sunrise representing hope

Read her story in her own words

A candid conversation about diagnosis, treatment, family, and finding meaning after a stage 4 diagnosis.

Read the Full Interview